Download e-book for iPad: AIDS and Respiratory Medicine by Jacques Chrétien, Donald A. Enarson (auth.), Alimuddin Zumla

By Jacques Chrétien, Donald A. Enarson (auth.), Alimuddin Zumla BSc MB ChB MSc PhD FRCP, Margaret Johnson MD, FRCP, Robert Miller MB FRCP (eds.)

ISBN-10: 0412601400

ISBN-13: 9780412601408

ISBN-10: 1489934464

ISBN-13: 9781489934468

In the 15 years of the received immunodeficiency syndrome (AIDS) pandemic a lot has been learnt approximately its traditional background and problems. it really is transparent that the lung is an important aim organ either for the human immunodeficiency virus (HIV), and a big selection of infectious and non-infectious pulmonary issues. loads of details at the epidemiology, microbiology, immunology, scientific good points, analysis and administration of those pulmonary problems has accrued prior to now 15 years. Given the large explosion in details, it's now well timed to compile this information during this 25-chapter quantity on AIDS and respiration drugs. The members to this quantity are widespread epidemiologists, medical professionals, microbiologists and scientists from Europe, united states and Africa. Professors Chretien and Enarson supply a masterful account of the epidemiology of lung issues of HIV. Drs Zumla, Rowland­ Jones and Professor McMichael provide an in depth precis of the lung immune responses to HIV. They define basic lung defenses and talk about the results of HIV an infection on them. The pulmonary radiological positive aspects of HIV and its issues as visible within the united states and Europe are illustrated through Professors Armstrong and Dee and this is often in comparison and contrasted by means of Professor Tshibwabwa-Tumba who brings jointly his giant event of chest X-rays in AIDS sufferers from imperative Africa. Drs O'Doherty and Miller care for the makes use of, and strength functions, of nuclear medication in imaging of the chest in AIDS patients.

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Within the 15 years of the received immunodeficiency syndrome (AIDS) pandemic a lot has been learnt approximately its traditional heritage and problems. it's transparent that the lung is a tremendous aim organ either for the human immunodeficiency virus (HIV), and a wide range of infectious and non-infectious pulmonary problems.

Extra resources for AIDS and Respiratory Medicine

Sample text

Thorax,47,513-18. , Chiengsong-Popov, R. and Weber, J. (1992) Is clearance of HIV1 viraemia at seroconversion mediated by neutralising antibodies? Lancet, 340, 1257-8. , Berry, N. et al. (1995) HIV-2-specific CTL activity is inversely related to proviral load. AIDS, 9, 555-59. , Hadida, F. et al. (1991) HIV-specific CTL against alveolar macrophages: specificities and down-regulation. Res. , 142,113-18. , Raphael, M. et al. (1988) Evidence for cytotoxic T lymphocyte alveolitis in human immunodeficiency virus infected patients.

Ann. Intern. , 103,704-709. , Katz, J. and Gottleib, M. (1986) Mechanism of defective NK cell activity in patients with acquired immunodeficiency syndrome (AIDS) and AIDS related complex. J. , 137, 1157-63. H. et al. (1994) Virus-specific CD8+ cytotoxic T-Iymphocyte activity associated with control of viremia in primary human immunodeficiency virus type 1 infection. J. , 68, 6103-10. L. M. (1984) Pulmonary cryptosporidiosis in the acquired immunodeficiency syndrome. JAMA, 252,89-90. N. and Bielefeldt-Ohmann, H.

These recruit PMNs from the circulating and marginating pools. They generate complement which amplifies host defenses and mediates immune mechanisms in the lung. Antibodydependent cellular cytotoxicity (ADCC) is an important mechanism by which monocytes recognize and lyse target cells. Macrophages play an important role in antigen recognition and presentation of antigens to T lymphocytes in association with its own major histocompatibility complex (MHC) class I and II products. Together with T cells, B cells and NK cells, the cell-to-cell interplay is a crucial pulmonary defense mechanism.

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AIDS and Respiratory Medicine by Jacques Chrétien, Donald A. Enarson (auth.), Alimuddin Zumla BSc MB ChB MSc PhD FRCP, Margaret Johnson MD, FRCP, Robert Miller MB FRCP (eds.)


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